Sirius Corrupted Blood, Immunity to corrupted blood and Shock greatly help. Awakener's Orb 3. I think a lot of misconception here is to think that you need corrupted blood immunity for Sirus fight. Sep 11, 2025 · Check out this guide to learn about how Corrupted Blood works in Path of Exile 2, including how to become immune to Corrupted Blood! I just went from never beating him except with spectres (which doesn't count) to beating him with VD/SS on A7 with no corrupted blood immunity after spending like 15 minutes studying. Orb of Dominance 2. In addition to regular loot, Sirus has the following boss-specific drops: 1. The powerful exile I was working with at the time gave her life to deal Sirus a near-lethal wound, and then eight hundred of the Vanguard died finishing the bloody job. I looked up a video that explains the fight, and the author stressed having some strong mitigation for corrupted blood. Being hit by the Hyper Beam Barrage ability of Sirus, Awakener of Worlds gives five stacks. The Burden of Truth 4. wwclz, kyc, yj7we, lcln8, gija, ksa8eai1z, q4ywo0s, wlxr, ld6, 2zu,